Abnormal breast enlargement in men is called gynecomastia. Sometimes it can cause discharge. This condition of boys during adolescence creates a very embarrassing situation. However, many boys reach puberty during the two years of puberty.
There are many causes of gynecomastia. However, the main reason is the difference and imbalance of sex hormones. Excess fat on the breasts often makes the breasts look bigger, but this is not gynecomastia. Gynecomastia can occur on one side or on both sides. There may be pain.
Gynecomastia is more common in neonates, adolescents, and before puberty. These abnormal breasts can be caused by taking various drugs including hormones, excess of estrogen hormone in the blood, decreased production of testosterone, androgen receptor defects, chronic kidney disease, liver cirrhosis, HIV, etc. In 25 percent of cases, no cause is known.
The first thing to note is whether this is happening due to side effects of any drug. Cimetidine, omiprazol, spironolactone, imatinib missylate, finasteride and some specific antipsychotic drugs cause problems. Some drugs act directly on breast tissue, while others interfere with dopamine and increase the secretion of prolactin from the pituitary gland. Androstenedione, used as a fortifying food supplement, increases the effectiveness of estrogen. Drugs used to treat prostate cancer, such as anti-androgens and DNRH analogs, cause gynecomastia. Marijuana is a cause of gynecomastia.
Estrogen levels are increased in testicular tumors and hyperthyroidism. Adrenal tumors increase levels of androstenedione. Decreased levels of the male sex hormone testosterone can lead to gynecomastia. Testosterone levels may decrease in testicular problems, hypothalamus or pituitary disease.
Misuse of anabolic androgenic steroids has the same effect. Gynecomastia can be caused by repeated use of some herbal oils and lotions in boys during adolescence.
In most cases, the breast returns to its previous state when the drug responsible for gynecomastia is stopped. Even then, if the condition is not normal, surgery is required. If you notice such changes in the breasts of boys, you should not be ashamed of it and should seek the help of a doctor.
Department of Endocrinology, Bangabandhu Sheikh Mujib Medical University
Source: Prothom Alo